Albumin is a protein made by the liver. A serum albumin test
measures the amount of this protein in the clear liquid portion of the blood.
Albumin can also be measured in the urine.
How the Test is Performed
A blood sample is needed.
How to Prepare for the Test
The health care provider may tell you to temporarily stop
taking certain medicines that can affect the test. Drugs that can increase
albumin levels include:
Anabolic steroids
Androgens
Growth hormone
Insulin
Do not stop taking any of your medicines without talking to
your provider first.
How the Test will Feel
When the needle is inserted to draw blood, some people feel
moderate pain. Others feel only a prick or stinging.
Afterward, there may be some throbbing or a slight bruise.
This soon goes away.
Why the Test is Performed
Albumin helps move many small molecules through the blood,
including bilirubin, calcium, progesterone, and medicines. It plays an
important role in keeping the fluid from the blood from leaking out into the
tissues.
This test can help determine if a patient has liver disease
or kidney disease, or if the body is not absorbing enough protein.
Normal Results
The normal range is 3.4 to 5.4 g/dL.
Normal value ranges may vary slightly among different
laboratories. Some labs use different measurements or test different samples.
Talk to your provider about the meaning of your specific test results.
What Abnormal Results Mean
A lower-than-normal level of blood albumin may be a sign of:
Kidney diseases
Liver disease (for example, hepatitis, or cirrhosis that may
cause ascites)
Decreased blood albumin may occur when your body does not
get or absorb enough nutrients, such as with:
After weight-loss surgery
Crohn disease
Low-protein diets
Celiac disease
Whipple disease
Increased blood albumin may be due to:
Dehydration
High protein diet
Having a tourniquet on for a long time when giving a blood
sample
Other conditions for which the test may be performed:
Burns (widespread)
Wilson disease
If you are receiving large amounts of intravenous fluids,
the result of this test may be inaccurate.
Albumin will be decreased during pregnancy.
Risks
There is very little risk involved with having your blood
taken. Veins and arteries vary in size from one patient to another and from one
side of the body to the other. Taking blood from some people may be more
difficult than from others.
Other risks associated with having blood drawn are slight,
but may include:
- Bleeding from where the needle was inserted
- Fainting or feeling lightheaded
- Hematoma (blood collecting under the skin)
- Infection (rare)
References
McPherson RA. Specific proteins. In: McPherson RA, Pincus
MR, eds. Henry's Clinical Diagnosis and Management by Laboratory Methods. 22nd
ed. Philadelphia, PA: Elsevier Saunders; 2011:chap 19.
Review Date 2/8/2015
Updated by: Laura J. Martin, MD, MPH, ABIM Board Certified
in Internal Medicine and Hospice and Palliative Medicine, Atlanta, GA. Also
reviewed by David Zieve, MD, MHA, Isla Ogilvie, PhD, and the A.D.A.M. Editorial
team.
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